Chemotherapy treatment uses medicine to weaken and destroy cancer cells in the body, including cells at the original cancer site and any cancer cells that may have spread to another part of the body. Chemotherapy, often shortened to just “chemo,” is a systemic therapy, which means it affects the whole body by going through the bloodstream. If you need chemo for a long time, surgeons would perform Subclavien Port Replacement (main vein to adminstrate chemotherapeutic agent) to protect small vessels of your forearm from side effects.